Sphingomyelin Synthase 1 anticorps

N° du produit ABIN4620352

L’anticorps Lapin Polyclonal anti-Sphingomyelin Synthase 1 a été validé pour WB, IHC (fro) et EIA. Il convient pour détecter Sphingomyelin Synthase 1 dans des échantillons de Humain et Souris.

Aperçu rapide pour Sphingomyelin Synthase 1 anticorps (ABIN4620352)

Antigène: Sphingomyelin Synthase 1 (SGMS1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sphingomyelin Synthase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Détail du produit anti-Sphingomyelin Synthase 1 anticorps

Specificité: This antibody detects Sphingomyelin Synthase 1, expressed in brain, heart, kidney, liver, muscle and stomach.

Purification: Ligand Affinity Chromatography

Immunogène: Synthetic peptide derived from the Human Sphingomyelin Synthase 1 protein

Information d'application

Indications d'application: ELISA. Western Blot: (5-10 g). Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline with 0.08 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Sphingomyelin Synthase 1

Antigène: Sphingomyelin Synthase 1 (SGMS1)

Autre désignation: TMEM23 / SGMS1

Sujet: A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus, Golgi membrane, multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.Synonyms: MOB, Medulla oblongata-derived protein, Phosphatidylcholine:ceramide cholinephosphotransferase 1, SMS1, Sphingomyelin synthase 1, Transmembrane protein 23

ID gène: 259230

NCBI Accession: NP_671512

UniProt: Q86VZ5

Pathways: Cellular Response to Molecule of Bacterial Origin